In The Long Dark, the only thing that can instantly end your run is a wolf struggle. This spreadsheet from 340+ wolf struggle tests has been a gift for my Twitch subs since summer, but today I decided to share it with everyone.
Read the first page conclusions for the shorthand. Happy Howly Days!
(I can only say the conclusions are valid for version 1.62-1.74. But Hinterland recently changed a core mechanic, and I think this makes the conclusions, and perhaps the elimination of some rumors