My Interloper character is at day 520 and ive just explored the whole region so here is my 2 cents
There wasn't a single pack of matches in any of the locations ive found yet
Very little by way of food. There's a bear spawn and a moose which basically kept me alive. I suppose you could use fishing but there isnt enough coal to keep a fire going for long enough to keep this up. I found 1 deer i think and a couple of rabbits
All the clothes are wrecked and the food is ruined but you can eat this as long as you are level 5
Best course of action ive found with the Timberwolves is to lure them then sprint backwards and take shots at them with the bow when they charge you. A couple of direct hits are all you need but its a very risky strategy.
No point going to the Cannery - its totally infested and very little loot.
The cold is mental as well - I found this zone far worse than any other and had to sprint from location to location. Blizzards were lasting 2 days for me too
I managed to avoid the wolves on the way out as i need to get more matches, arrows and repair my clothes before going back
Apart from the fun of exploring a new zone i cant see any reward in interloper players going there. I guess if you've run out of birch or maple then a loot of the area will reap rewards. Avoid the cannery though. Did i mention avoiding the cannery?